For an updated list of publications go to:

2010 - present

Knop M.; Engi P.; Lemnaru R; Seebeck F.P.
"In Vitro Reconstitution of Formylglycine-Generating Enzymes Requires Copper(I)"
Chembiochem. 2015, in print


Vit A.; Mashabela, G.T.; Blankenfeldt W.; Seebeck F.P.
"Structure of the Ergothioneine-Biosynthesis Amidohydrolase EgtC"
Chembiochem. 2015, 16, 1490 - 1496


Goncharenko K.V.; Vit A.; Blankenfeldt W.; Seebeck F.P.
"Structure of the Sulfoxide Synthase EgtB from the Ergothioneine Biosynthetic Pathway"
Angew Chem Int Ed Engl. 2015, 54, 2821 - 2824

Vit A.; Misson L.; Blankenfeldt W.; Seebeck FP.
"Ergothioneine Biosynthetic Methyltransferase EgtD Reveals the Structural Basis of Aromatic Amino Acid Betaine Biosynthesis"
Chembiochem. 2015, 16, 119 - 125

Vit A.; Misson L.; Blankenfeldt W.; Seebeck F.P.
"Crystallization and preliminary X-ray analysis of the ergothioneine-biosynthetic methyltransferase EgtD"
Acta Crystallogr F Struct Biol Commun. 2014, 70, 676 - 680

Mashabela, G.T.; Seebeck, F.P.
"Substrate specificity of an oxygen dependent sulfoxide synthase in ovothiol biosynthesis"
Chem. Commun. 2013, 49, 714 - 7716


Seebeck, F.P.
"Thiohistidine biosynthesis"
CHIMIA. 2013, 67, 333 - 336


Hofmann, F.T.; Szostak, J.W.; Seebeck, F.P.
"In vitro selection of functional lantipeptides"
J. Am. Chem. Soc. 2012, 134, 8038 - 8041

Amrein, B.; Schmid, M.; Collet, G.; Cuniasse, P.; Gilardoni, F.; Seebeck, F.P.; Ward, T.R.
"Identification of two-histidines one-carboxylate binding motifs in proteins amenable to facial coordination to metals"
Metallomics. 2012 2012, 4, 379 - 388

Frank T. Hofmann, F.T.; Lindemann, C.; Salia, H.; Adamitzki, P.; Karanicolas, J.; Seebeck, F.P.
"Synthetic phosphoarginine containing peptides as artificial SH2 ligands"
Chem. Commun. 2011, 47, 10335 - 10337

fig 4

Seebeck, F. P.; Ricardo, A.; Szostak, J. W.
"Artificial lantipeptides from in vitro translations"
Chem. Commun. 2011, 47, 6141 - 5143

fig 3

Braunshausen, A.; Seebeck, F.P.
"Identification and characterization of the first Ovothiol biosynthetic Enzyme"
J. Am. Chem. Soc. 2011, 133, 1757 - 1759

fig 2

Seebeck, F.P.
"In vitro reconstitution of mycobacterial ergothioneine biosynthesis"
J. Am. Chem. Soc. 2010, 132, 6632 - 6633.

fig 1

2001 - 2009

Müller, R.; Debler, E. W.; Steinmann, M.; Seebeck, F. P.; Wilson, I. A.; Hilvert, D.
"Bifunctional catalysis of proton transfer at an antibody active site"
J. Am. Chem. Soc. 2007, 129, 460-461.

Seebeck, F. P.; Guainazzi A.; Amoreira C.; Kim K. Baldridge, K. K.; Hilvert. D.
"Stereoselectivity and expanded substrate scope of an engineered PLP-dependent aldolase"
Angew. Chem. Int. Ed. Engl. 2006, 45, 6824 - 6826.

Seebeck, F. P.; Szostak, J. W.
"Ribosomal synthesis of dehydroalanine containing peptides"
J. Am. Chem. Soc. 2006, 128, 7150 - 7151.

Woycechowsky, K. J.; Seebeck, F. P.; Hilvert, D.
"The tunnel of a symmetric, homo-oligomeric protein with remarkable resilience to multiple mutations"
Prot. Sci. 2006, 15, 1106 - 1114.

Seebeck, F. P.; Woycechowsky, K. J.; Zhuang, W.; Rabe, J. P.; Hilvert, D.
"A simple tagging system for protein encapsulation"
J. Am. Chem. Soc. 2006, 128, 4516 - 4517.

Debler, E. W.; Ito, S.; Seebeck, F. P.; Heine, A.; Hilvert, D; Wilson, I. A.
"Crystal structures of the highly efficient catalytic elimination antibody 34E4 reveal its reaction mechanism"
Proc. Natl. Acad. Sci. USA, 2005, 102, 4984 - 4989.

Seebeck, F. P.; Hilvert, D.
"Positional ordering of reacting groups contributes significantly to the efficiency of proton transfer at an antibody active site"
J. Am. Chem. Soc. 2005, 127, 1307 - 1312.

Seebeck, F. P.; Hilvert, D.
"Conversion of a PLP-dependent racemase into an aldolase by a single active site mutation"
J. Am. Chem. Soc. 2003, 125, 10158 - 10159.

Knapp, M. J.; Seebeck, F. P.; Klinman, J. P.
"Steric control of oxygenation regiochemistry in soybean lipoxygenase-1"
J. Am. Chem. Soc. 2001, 123, 2931 - 2932.