Anna Paola Pelliccioli and Jakob Wirz "Photoremovable Protecting Groups: Reaction Mechanisms and Applications", Photochem. Photobiol. Sci., 2002, 1, 441-458.


Abstract: Photolabile protecting groups enable biochemists to control the release of bioactive compounds in living tissue. 'Caged compounds' (photoactivatable bioagents) have become an important tool to study the events that follow chemical signalling in, e.g., cell biology and the neurosciences. The possibilities are by no means exhausted. Progress will depend on the development of photoremovable protecting groups that satisfy the diverse requirements of new applications a challenging task for photochemists.