Publications

2012

 

  • R. S. Erdmann, H. Wennemers "Conformational Stability of Collagen Triple Helices Functionalized in the Yaa Position by Click Chemistry"
    Org. Biomol. Chem. 2012, 10, 1982-1986.
[abstract]
  • G. Upert, F. Bouillère, H. Wennemers "Correlating Molecular with Nanoscopic Dimensions - Oligoprolines as Scaffolds for the Formation of Ag-Nanoparticles in Defined Sizes"
    Angew. Chem. Int. Ed. 2012, 51, 4231-4234.
[abstract]
  • J. Duschmalé, H. Wennemers "Adapting to Substrate Challanges: Peptides as Catalysts for Conjugate Addition Reactions of Aldehydes to α,β-Disubstituted Nitroolefins"
    Chem. Eur. J. 2012, 18, 1111-1120.
[abstract]
  • P. Clerici, H. Wennemers "Mono Thiomalonates as Thioester Enolate Equivalents – Enantioselective 1,4-Addition Reactions to Nitroolefins under Mild Conditions"
    Org. Biomol. Chem. 2012, 10, 110-113.


[abstract]
2011

 

  • H. Wennemers "Asymmetric Catalysis with Peptides"
    Chem. Commun. 2011, 47, 12036-12041.
[abstract]
  • R. S. Erdmann, H. Wennemers "Importance of Ring Puckering versus Interstrand Hydrogen Bonds for the Conformational Stability of Collagen"
    Angew. Chem. Int. Ed. 2011, 50, 6835-6838.
[abstract]
  • Y. Arakawa, M. Wiesner, H. Wennemers "Efficient Recovery and Reuse of an Immobilized Peptidic Organocatalyst"
    Adv. Synth. Catal. 2011, 353, 1201-1206.
[abstract]
  • Y. Nagel, M. Kuemin, H. Wennemers "Functionalizable Oligoprolines as Molecular Scaffolds"
    Chimia 2011, 65, 264-267.
[abstract]
  • M. Messerer, H. Wennemers "Reversing the Enantioselectivity of a Peptidic Catalyst by Changing the Solvent"
    Synlett 2011, 499-502.

[abstract]
2010

 

  • R. S. Erdmann, H. Wennemers, "Functionalizable Collagen Model Peptides"
    J. Am. Chem. Soc. 2010, 132, 13957–13959.
[abstract]
  • M. Kuemin, Y. A. Nagel, S. Schweizer, F. W. Monnard, C. Ochsenfeld, H. Wennemers, "Tuning the cis:trans Conformer Ratio of Xaa-Pro Amide Bonds by Intramolecular Hydrogen Bonds - Effect on the Stability of the PPII Helix"
    Angew. Chem. Int. Ed. 2010, 49, 6324 –6327.
[abstract]
  • M. Kuemin, J. Engel, H. Wennemers, "Temperature Induced Transition between Polyproline I and II Helices – Quantitative Fitting of Hysteresis Effects"
    J. Pept. Sci. 2010, 16, 596-600.
[abstract]
  • G. Upert, C. A. Merten, H. Wennemers "Nanoliter Plates - Versatile Tools for the Screening of Split-and-Mix Libraries On-bead and Off-bead"
    Chem. Commun. 2010, 46, 2209-2211.
[abstract]
  • M. Wiesner, H. Wennemers, “Peptide Catalyzed Conjugate Addition Reactions of Aldehydes to Nitroolefins”
    Synthesis 2010, 1568-1571.
[abstract]
  • P. Krattiger, N. Nassif, A. Völkel, Y. Mastai, H. Wennemers, H. Cölfen "Investigation of active crystal morphogenesis peptide sequences from peptide libraries by crystallization on peptide functionalized beads"
    Colloids and Surfaces A: Physicochemical and Engineering Aspects 2010,354, 218-225.
[abstract]
  • M. Wiesner, G. Upert, G. Angelici, H. Wennemers "Enamine Catalysis with Low Catalyst Loadings – High Efficiency via Kinetic Studies"
    J. Am. Chem. Soc. 2010, 132, 6-7.

[abstract]
[cover]
2009

 

  • M. Kuemin, S. Schweizer, C. Ochsenfeld, H. Wennemers "Effects of Terminal Functional Groups on the Stability of the Polyproline II Structure – A Combined Experimental and Theoretical Study"
    J. Am. Chem. Soc. 2009, 131, 15474–15482.
[abstract]
  • M. Wiesner, M. Neuburger, H. Wennemers "Tripeptides of the Type H-D-Pro-Pro-Xaa-NH2 as Catalysts for Asymmetric 1,4-Addition Reactions: Structural Requirements for High Catalytic Efficiency"
    Chem. Eur. J. 2009, 15, 10103-10109.
[abstract]
  • K. Belser, T. V. Slenters, C. Pfumbidzai, G. Upert, L. Mirolo, K. M. Fromm, H. Wennemers " Silver Nanoparticle Formation in Different Sizes Induced by Peptides Identified within Split-and-Mix Libraries"
    Angew. Chem. Int. Ed., 2009, 48, 3661-3664.      recognized as Hot Paper
[abstract]
  • R. S. Erdmann§, M. Kümin, H. Wennemers "(4R)- and (4S)-Azidoprolines – Conformation Directing Amino Acids and
    Sites for Functionalization"
    Chimia 2009, 63, 197-200.

    §On the occasion of the poster award from the Swiss Chemical Society at the Fall Meeting 2008.
[abstract]
  • R. S. Erdmann, H. Wennemers "Synthesis of Fmoc-Pro-Hyp(TBDPS)-Gly-OH and its Application as a Versatile Building Block for the Preparation of Collagen Model Peptides"
    Synthesis 2009, 143-147.


[abstract]
2008

 

  • M. Wiesner, J. D. Revell, S. Tonazzi, H. Wennemers "Peptide Catalyzed Asymmetric Conjugate Addition Reactions of Aldehydes to Nitroethylene – A Convenient Entry into γ2-Amino Acids"
    J. Am. Chem. Soc. 2008, 130, 5610-5611.

[abstract]

  • J. D. Revell, H. Wennemers "Investigating Sequence Space: How Important is the Spatial Arrangement of Functional Groups in the Asymmetric Aldol Reaction Catalyst H-Pro-Pro-Asp-NH2?"
    Adv. Synth. Catal. 2008, 350, 1046-1054.

[abstract]

  • C. F. J. Faul, P. Krattiger, B. Smarsly, H. Wennemers "Ionic Self-Assembled Molecular Receptor-Based Liquid Crystals with Tripeptide Recognition Capabilities"
    J. Mater. Chem. 2008, 18, 2962-2967.

[abstract]

  • M. Wiesner, J. D. Revell, H. Wennemers “Tripeptides as Efficient Asymmetric Catalysts for 1,4-Addition Reactions of Aldehydes to Nitroolefins - A Rational Approach”,
    Angew. Chem. Int. Ed. 2008, 47, 1871-1874.

[abstract]

  • X. Y. Gong, D. Dobrunz, M. Kümin, M. Wiesner, J. D. Revell, H. Wennemers, P. Hauser, "Distinguishing stereoisomers of di-, tri-, and tetrapeptides using capillary electrophoresis with contactless conductivity detection",
    J. Sep. Sci.
    2008, 31, 565-573.


[abstract]

2007

 

  • J. Bernard, H. Wennemers,  "Macrocyclic Diketopiperazine Receptors – Effect of Macrocyclization on the Binding Properties of Two-armed Receptors"
    Org. Lett.
    2007, 9, 4283-4286.

[abstract]

  • C. Aprile, F. Giacalone, M. Gruttadauria, A. Mossuto Marculescu, R. Noto, J. D. Revell, H. Wennemers "New ionic liquid-modified silica gels as recyclable materials for L-proline- or H-Pro-Pro-Asp-NH2-catalyzed aldol reactions”,
    Green Chemistry
    2007, 9, 1328-1334.

[abstract]

  • J. Lubkoll, H. Wennemers "Mimicry of Polyketide Synthases - Enantioselective 1,4-Addition Reactions of Malonic Acid Half Thioesters to Nitroolefins", 
    Angew. Chem. Int. Ed. Engl.
    2007, 46, 6841-6844.

[abstract]

  • J. D. Revell, H. Wennemers "Functional Group Requirements for Catalysis of Aldol Reactions with the Peptide H-Pro-Pro-Asp-NH2",
    Tetrahedron
    2007, 63, 8420-8424.

[abstract]

  • H. Wennemers "Peptides as Asymmetric Catalysts for Aldol Reactions",
    Chimia 2007, 61, 276-278.

 

  • J. D. Revell, H. Wennemers "Peptidic Catalysts Developed by Combinatorial Screening Methods",
    Curr. Opin. Chem. Biol. 2007, 11, 269-278.

[abstract]

  • J. D. Revell, H. Wennemers "Identification of Catalysts in Combinatorial Libraries",
    Top. Curr. Chem.
    2007, 277, 251-266.

[abstract]

  • M. Kümin, L.-S. Sonntag, H. Wennemers "Azidoproline Containing Helices – Stabilization of the Polyproline II Structure by a Functionalizable Group",
    J. Am. Chem. Soc.
    2007, 129, 466-467.

[abstract]

  • A. R. Stettler, P. Krattiger, H. Wennemers, M. Schwarz “Electrophoretic Affinity Measurements on Microchip – Determination of Binding Affinities between Diketopiperazine Receptors and Peptide Ligands”,
    Electrophoresis
    2007, 28, 1832-1838.



[abstract]

2006

 

  • L.-S. Sonntag, S. Schweizer, C. Ochsenfeld, H. Wennemers “The “Azido Gauche Effect“ – Implications for the Conformation of Azidoprolines“,
    J. Am. Chem. Soc.
    2006, 128, 14697-14703.

[abstract]

  • J. Grun, J. D. Revell, M. Conza, H. Wennemers, “Peptide–Polyethylene Glycol Conjugates: Synthesis and Properties of Peptides Bearing a C-terminal Polyethylene Glycol Chain“,
    Bioorg. Med. Chem.
    2006, 14, 6197-6201.

[abstract]

  • J. D. Revell, D. Gantenbein, P. Krattiger, H. Wennemers, “Solid-supported and Pegylated H-Pro-Pro-Asp-NHR as Catalysts for Asymmetric Aldol Reactions“,
    Biopolymers (Pept. Sci
    .) 2006, 84, 105-113.


[abstract]

2005

 

  • P. Krattiger, R. Kovasy, J. D. Revell, H. Wennemers "Using Catalyst-Substrate Coimmobilization for the Discovery of Catalysts for Asymmetric Aldol Reactions in Split-and-Mix Libraries",
    QSAR Comb. Sci.
    2005, 24, 1158-1163.

[abstract]

  • M. Nold, K. Koch, H. Wennemers "Acid-Rich Peptides are Prone to Damage under Fenton Conditions - Split-and-Mix Libraries for the Detection of Selective Peptide Cleavage",
    Synthesis
    2005, 1455-1458.

[abstract]

  • P. Krattiger, R. Kovasy, J. D. Revell, S. Ivan, H. Wennemers "Increased Structural Complexity Leads to Higher Activity: Peptides as Efficient and Versatile Catalysts for Asymmetric Aldol Reactions",
    Org. Lett.
    2005, 7, 1101-1103.

[abstract]

  • P. Krattiger, H. Wennemers "Water-soluble Diketopiperazine Receptors: Selective Recognition of Peptides in Aqueous Solution",
    Synlett
    2005, 4, 706-708.

[abstract]

  • J.W. Lörgen, P. Krattiger, C. Kreuz, H. Wennemers, J. Bargon, "Diketopiperazine Receptors: Highly Selective Layers for Gravimetric Sensors",
    Sensors and Actuators B: Chemical
    2005, 107, 366-371.

 

2004

 

  • M. Nold, H. Wennemers "Peptide Damage under Fenton Conditions is Sequence Dependent",
    Chem. Commun.
    2004, 16, 1800-1801.

[abstract]

  • L.-S. Sonntag, S. Ivan, M. Langer, M.M. Conza, H. Wennemers, "Functionalised Cyclotriproline - A Bowl-shaped Tripodal Scaffold",
    Synlett
    2004, 1270-1272.

[abstract]

  • H. Wennemers, "Combinatorial Methods for the Discovery of Catalysts", in "Highlights in Bioorganic Chemistry", Wiley-VCH Weinheim 2004, edited by C. Schmuck and H. Wennemers, 436-445.


 

2003

 

  • H. Wennemers, "Peptide Receptors - From Selective Molecular Recognition towards Catalytic Activity",
    Chimia
    2003, 57, 237-240. (review)
 
  • P. Krattiger, C. McCarthy, A. Pfaltz, H. Wennemers “Catalyst-Substrate Coimmobilization: A Strategy for Catalyst Discovery in Split-and-Mix Libraries”, Angew. Chem. Int. Ed. Engl. 2003, 42, 1722-1724,
    Angew. Chem.
    2003, 115, 1763-1766.

[abstract]

  • H. Wennemers, M. Conza, “Determination of Binding Affinities on Solid Supports: Influence of the Loading and the Nature of the Solid Support”,
    Chem. Commun.
    2003, 7, 866-867.

[abstract]

  • H. Wennemers, M. Nold, M. Conza, K. J. Kulicke, M. Neuburger “Flexible but with a Defined Turn - Influence of the Template on the Binding Properties of Two-armed Receptors”,
    Chem Eur. J.
    2003, 9, 442-448.

[abstract]

2002

 

  • M. Conza, H. Wennemers “Binding of Diketopiperazine Receptors to Sidechain-protected Peptides",
    J. Org. Chem. 2002, 67, 2696-2698.

[abstract]

2001

 

  • H. Wennemers, M. Conza, M. Nold, P. Krattiger “Diketopiperazine Receptors - A Novel Class of Highly Selective Receptors for Binding Small Peptides”,
    Chem. Eur. J. 2001, 7, 3342-3347.

[abstract]

  • H. Wennemers, "Combinatorial Chemistry: A Tool for the Discovery of New Catalysts",
    Comb. Chem. High Throughput Screening
    2001, 4, 273-285.(Review)

 

2000-1994

 

  • M. Conza, M. Nold, H. Wennemers "Sequence-selective Binding of Small Peptides by Two-armed Receptors",
    ECSOC-4 2000, 1334-1337.

 

  • H. Wennemers, “34th EUCHEM Conference on Stereochemistry, Bürgenstock, 1999”,
    Chimia
    1999, 53, 403-407. (Conference Report)

 

  • H. Wennemers, “Towards the Development of Sequence-Selective Artificial Proteases”,
    Chimia 1999, 53, 229-230.

 

  • G. Quinkert, S. Scherer, D. Reichert, H.P. Nestler, H. Wennemers, A. Ebel, K. Urbahns, K. Wagner, K.-P. Michaelis, G. Wiech, G. Prescher, B. Bronstert, B.-J. Freitag, I. Wicke, D. Lisch, P. Belik, T. Crecelius, D. Höchstermann, G. Zimmermann, J.W. Bats, G. Dürner, D. Rehm, “Stereoselective Ring Opening of Electronically Excited Cyclohexa-2,4-dienones: Cause and Effect”,
    Helv. Chim. Acta 1997, 80, 1683-1772.

 

  • F. Gasparrini, D. Misiti, W.C. Still, C. Villani, H. Wennemers, “Enantioselective and Diastereoselective Binding Study of Silica Bound Macrobicyclic Receptors by HPLC”,
    J. Org. Chem.
    1997, 62, 8221-8224.

[DOI]

  • H.P. Nestler, H. Wennemers, R. Sherlock, D.L.Y. Dong, “Microautoradiographic Identification of Receptor-LigandInteractions in Bead-Supported Combinatorial Libraries”,
    Bioorg. Med. Chem. Lett.
    1996, 6, 1327-1330.

 

  • M. Maletic, H. Wennemers, D.Q. McDonald, R.C. Breslow, W.C. Still, "Selective Binding of the Dipeptides L-Phe-D-Pro and D-Phe-L-Pro to b-cyclodextrin",
    Angew. Chem. Int. Ed. Engl.
    1996, 35, 1490-1492.

 

  • H. Wennemers, S.S. Yoon, W.C. Still, “Cyclooligomeric Receptors Based on Trimesic Acid and 1,2-Diamines. Minimal Structure for Sequence-Selective Peptide Binding”,
    J. Org. Chem.
    1995, 60, 1108-1109.

 

  • H. Wennemers, W.C. Still, “Peptide Complexation in Water. “Sequence Selective Binding with Simple Dye Molecules”,
    Tetrahedron Lett.
    1994, 35, 6413-6416.