Colloids and Surfaces B: Biointerfaces 2009, 74, 419-425           Abstract



Benoît Y. Michel and Peter Strazewski

Total syntheses of a conformationally locked North-type methanocarba puromycin analogue and its dinucleotide derivative

Chemistry - A European Journal 2009, 15, 6244-6257           Abstract               Supporting Information (PDF, 14.7 MB)



Hisao Saneyoshi, Benoît Y. Michel, Yongseok Choi, Peter Strazewski and Victor E. Marquez

Synthesis of Conformationally Locked Versions of Puromycin Analogues

Journal of Organic Chemistry 2008, 73, 9435-9438           Abstract               Supporting Information (PDF, 9.5 MB)



Benoît Y. Michel, Kollappillil S. Krishnakumar, Magnus Johansson, Måns Ehrenberg and Peter Strazewski

Structural and functional prerequisites for ribosomal nascent peptide acceptors: Attempts to decipher the nature of the ribosome's catalysis of peptide bond formation

Nucleic Acids Symposium Series 2008, 52, 33-34 (open access)



Benoît Y. Michel, Kollappillil S. Krishnakumar and Peter Strazewski

Synthesis of a xylo-Puromycin Analogue

Synlett 2008, 2461-2464             Abstract                             Supporting Information (PDF, 5 MB)



Carole Lamy, Jérôme Lemoine, Denis Bouchu, Peter Goekjian and Peter Strazewski

Glutamate-Glycine and Histidine-Glycine Co-oligopeptides: Batch Co-oligomerization versus Pulsed Addition of N-Carboxyanhydrides

ChemBioChem 2008, 9, 710-713             Abstract                      Supporting Information (PDF, 4.3 MB)



Benoît Y. Michel and Peter Strazewski

Synthesis of (–)-neplanocin A with the highest overall yield via an efficient Mitsunobu coupling

Tetrahedron 2007, 63, 9836-9841             Abstract                      Supporting Information (PDF, 5.8 MB)



Basic Questions about the Origin of Life
Question 6 : The Genetic Code

A panel contribution by Peter Strazewski

How did translation occur ?

Origin of Life and Evolution of Biospheres 2007, 37, 399-401
Abstract            PowerPoint Presentation (1.1 MB)



Adib Charafeddine, Hubert Chapuis and Peter Strazewski

Facile and rapid access to inosine puromycin analogues through the use of adenylate deaminase

Organic Letters 2007,9, 2787-2790    Abstract



Adib Charafeddine, Wissam Dayoub, Hubert Chapuis and Peter Strazewski

First synthesis of 2'-deoxyfluoropuromycin analogues: Experimental insight into the mechanism of the Staudinger reaction

Chemistry - A European Journal 2007,13, 5566-5584    Abstract    Supporting Information (PDF, 10.4 MB)



Hubert Chapuis and Peter Strazewski

Shorter Puromycin Analog Synthesis by Means of an Efficient Staudinger-Vilarrasa Coupling

Tetrahedron 2006, 62, 12108-12115    Abstract



Adina Lazar, Anthony Coleman, Silvia Terenzi, and Peter Strazewski

Observation of the Formation of Supported Bilayers by Amphiphilic Peptidyl-RNA

Chemical Communications 2006, (1), 63-65    Abstract



Peter Strazewski :

Letter to C&EN à propos "Channeling the future"

Chemical & Engineering News, March 1, 2004
Volume 82, Number 9, pp. 4-5, 45.   

Full Text - HTML



Nhat Quang Nguyen-Trung, Silvia Terenzi, Gerd Scherer, and Peter Strazewski

High yield immobilisation of a puromycin analogue for the solid support synthesis of aminoacyl-tRNA fragments

Organic Letters 2003, 5, 2603-2606          Abstract          Supporting Information



Silvia Terenzi, Ewa Biala, Nhat Quang Nguyen-Trung, and Peter Strazewski

Amphiphilic 3'-Peptidyl-RNA Conjugates

Angewandte Chemie 2003, 42, 3015-3018
Angewandte Chemie Int. Ed. 2003, 42, 2909-2912

Abstract Full Text Supporting Information

PhD Thesis on the subject (S. Terenzi, University of Basel, 2003): PDF 10.6 MB



Nhat Quang Nguyen-Trung, Oliver Botta, Silvia Terenzi and Peter Strazewski

A practical route to 3'-amino-3'-deoxyadenosine derivatives and puromycin analogs

Journal of Organic Chemistry 2003, 68, 2038-2041.   

Abstract
Full Text - HTML, PDF, Supporting Information



Peter Strazewski

Thermodynamic Correlation Analysis: Hydration and Perturbation Sensitivity of RNA Secondary Structures

Journal of the American Chemical Society
2002, 124, 3546-3554.    Abstract
Full Text - HTML, PDF, Supporting Information



Ewa Biala and Peter Strazewski

Internally Mismatched RNA: pH and Solvent Dependence of the Thermal Unfolding of tRNA^Ala Acceptor Stem Microhairpins

Journal of the American Chemical Society
2002, 124, 3540-3545.    Abstract
Full Text - HTML, PDF, Supporting Information



Yongseok Choi, Clifford George, Peter Strazewski, and Victor E. Marquez

Synthesis of a Conformationally Locked Version of Puromycin Amino Nucleoside

Organic Letters 2002, 4, 589-592.    Abstract

Full Text - HTML, PDF, Supporting Information



Nhat Quang Nguyen Trung, Peter Strazewski,*
Martin Olsson and Måns Ehrenberg

Ab initio calculations of puromycin and some synthetic analogs

Nucleosides, Nucleotides and Nucleic Acids 2001, 20, 383-384.    Abstract



Peter Strazewski:

W obronie chemii

Nauka 2000, 1 , 109-125.

(Quarterly journal of the Polish Academy of Sciences, PAN)

Polski tekst z ilustracjami (PDF 10 MB)     



Elisabeth Moyroud, Ewa Biala, Peter Strazewski:

Synthesis and enzymatic digestion of an RNA nonamer in both enantiomeric forms

Tetrahedron 2000, 56, 1475-1484



Peter Strazewski, Ewa Biala, Kay Gabriel and William H. McClain:

The Relationship of Thermodynamic Stability at a G^.U Recognition Site to tRNA Aminoacylation Specificity

RNA 1999, 5, 1490-1494.    Abstract Full Article - PDF



Peter Strazewski:

A Pleading For Chemistry

European Chemistry Chronicle 1999, 4/1

A more recent article that was obviously inspired by A Pleading For Chemistry, albeit on the far pragmatic and educational end of the line of thoughts - with no reference to the main message of A Pleading which is the necessity of forced (well funded) and widespread scientific studies on Chemical Evolution (Systems Chemistry) -, was written by Raymond G. Wallace and published in Chemistry Education: Research and Practice 2003, 4, 83-96 : "Rethinking the education of chemists - The Odyssey is over, time for action!"

Elisabeth Moyroud, Oliver Botta, Peter Strazewski:

L–Ribonucleosides for racemic RNA

Nucleosides & Nucleotides 1999, 18, 693-696.    Abstract



Oliver Botta, Peter Strazewski:

Synthesis of an alanyladenosine analog

Nucleosides & Nucleotides 1999, 18, 721-724.   Abstract



Ewa Biala, William H. McClain, Peter Strazewski:

Thermodynamics of Site–Specific Variant tRNA^Ala Acceptor Stem Microhairpins

Nucleosides & Nucleotides 1999, 18, 1575-1576.    Abstract



Ewa Biala, Oliver Botta, Elisabeth Moyroud, Peter Strazewski:

Ribonucleosides, Aminoacyl–, and Peptidyl–RNA: Synthesis, Thermodynamics, and Structure

Chimia 1999, 53 (5), 226-227    Abstract



Elisabeth Moyroud, Peter Strazewski:

L-Ribonucleosides from L–Xylose

Tetrahedron 1999, 55, 1277-1284    Abstract



Oliver Botta, Elisabeth Moyroud, Cinta Lobato, Peter Strazewski:

Synthesis of 3'–azido– and 3'–amino–3'–deoxyadenosine in both enantiomeric forms

Tetrahedron 1998, 54, 13529-13546.    Abstract



Sigmund Gunzenhauser, Ewa Biala, Peter Strazewski:

Tetraethylene–derived spacer for oligonucleotide synthesis

Tetrahedron Letters 1998, 39, 6277-6280.    Abstract



Peter Strazewski:

Braucht es ein Plädoyer für Chemie?

Chimia 1997, 51(3), 69-75.   

Originalfassung in deutscher Sprache



Antonio Amantea, Matthias Henz, Peter Strazewski:

Synthesis of (¹⁵N₂)[¹⁷O]Urea, (¹⁵N₂)[O²,O⁴–¹⁷O₂]Uridine and (¹⁵N₃)[O²–¹⁷O]Cytidine

Helvetica Chimica Acta 1996, 79, 244-254.    Abstract



Peter Strazewski:

Calculating the Thermodynamics of Weakly Hydrogen–Bonded Complexes from Heteronuclear NMR Data: Base Pairing Stabilities of a 5–Methyl–(¹⁵N₂)[O²,O⁴–¹⁷O₂]uridine Derivative and Structural Implications

Helvetica Chimica Acta 1995, 78, 1112-1143.    Abstract

Link to the Wolfram Research Information Centre



Antonio Amantea, Markus Walser, Urs Séquin, Peter Strazewski:

Synthesis and ¹⁵N– and ¹⁷O–NMR Spectroscopy of 5–Methyl–(¹⁵N₂)–[O²,O⁴–¹⁷O₂]uridine

Helvetica Chimica Acta 1995, 78, 1106-1111.    Abstract



Annette Niemann, Monica Meyer, Thomas Engeloch, Oliver Botta, Alfons Hädener, Peter Strazewski:

Biosynthetic Production of [N²,1,3,7,9–¹⁵N]Guanosine and [1,3,7,9–¹⁵N]Inosine and Conversion into [N⁶,1,3,7,9–¹⁵N]Adenosine for Structure Elucidation of RNA by Heteronuclear NMR

Helvetica Chimica Acta 1995, 78, 421-439.    Abstract



Peter Strazewski:

Recent Studies on the Synthesis, Structure and Function of Nucleic Acids

Habilitation Thesis 1994, University of Basel.    Abstract



William B.T. Cruse, Pedro Saludjian, Ewa Biala, Peter Strazewski, Thierry Prangé, Olga Kennard:

The Structure of a Mispaired RNA Double Helix at 1.6 Å Resolution and Implications for Prediction of RNA Secondary Structure

Proceedings of the National Academy of Sciences of the USA 
1994, 91, 4160-4164.    Abstract



Felix Stolz, Peter Strazewski, Christoph Tamm, Markus Neuburger, Margareta Zehnder:

New Chiral alpha-Benzyloxyacryliron(II) Complex for Asymmetric Synthesis of alpha,alpha-Dialkyl-alpha-hydroxycarbonyl Compounds

Angewandte Chemie Int. Ed. Engl. 1992, 31, 193-195.    Abstract



Thomas Kienzler, Peter Strazewski, Christoph Tamm:

A New Synthesis of Coprine and O-Ethylcoprine

Helvetica Chimica Acta 1992, 75, 1078-1084    Abstract



Harald Eschenhof, Peter Strazewski, Christoph Tamm:

A new synthesis of 3-deazathymidine and of a related phosphoramidite synthon

Tetrahedron 1992, 48, 6225-6230



Peter Strazewski:

Psoralen Mutagenesis by Transient Misalignment?

Journal of Theoretical Biology 1991, 151, 429-431.    Abstract



Thomas Kienzler, Peter Strazewski, Christoph Tamm:

Synthesis of 1-Aminocyclopropanol by Anodic Oxidation

Synlett 1991, 737-738.    Abstract



Peter Strazewski:

The Biological Equilibrium of Base Pairs

Journal of Molecular Evolution 1990, 30, 116-124.    Graphical Abstract



Peter Strazewski, Christoph Tamm:

Replication Experiments with Nucleotide Base Analogs

Angewandte Chemie Int. Ed. Engl. 1990, 29, 36-57.    Abstract



Peter Strazewski:

Mispair formation in DNA can involve rare tautomeric forms in the template

Nucleic Acids Research 1988, 16, 9377-9398    Abstract



Peter Strazewski:

¹³C-NMR spectra of 2'-deoxycytidine and 3-deaza-2'-deoxycytidine.

Nucleic Acids Research 1988, 16, 5191   



Peter Strazewski, Christoph Tamm:

Eine einfache Synthese von 1-Amino-cyclopropan-1-carbonsäure

Synthesis 1987, 298-299.    Abstract



Peter Strazewski, Christoph Tamm:

Insight into the Behaviour of a Lithium Enolate in Solution

Helvetica Chimica Acta 1986, 69, 1041-1051.    Abstract



Tibur Schmidlin, Remo Gamboni, Peter Strazewski, Christoph Tamm:

Approaches to the synthesis of cytochalasans. Part 5. Studies on the selectivity of the Diels-Alder reaction leading to the tetrahydroiso-indolinone sub-unit

Helvetica Chimica Acta 1983, 66, 1796-1805.    Abstract