By project

Publications


27.
Direct Transformation of Esters into Heterocyclic Fluorophores
C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2018, 57, accepted for publication.


26.
Stereoselective Arene-Forming Aldol Condensation: Catalyst-Controlled Synthesis of Axially Chiral Compounds
R. M. Witzig, D. Lotter, V. C. Fäseke, C. Sparr*
Chem. Eur. J. 2017, 23, 12960–12966.



25.
Catalytic Arene-forming Aldol Condensation: Stereoselective Synthesis of Rotationally Restricted Aromatic Compounds
V. C. Fäseke, R. M. Witzig, A. Link, D. Lotter, C. Sparr*
Chimia 2017, 71, 596–599. Werner Prize 2017

24.
A 1,5-Bifunctional Organomagnesium Reagent for the Synthesis of Disubstituted Anthracenes and Anthrones
A. Link, C. Fischer, C. Sparr*
Synthesis 2017, 49, 397–402. Special issue dedicated to Prof. Dieter Enders (invited)


23.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Axially Chiral Aromatic Amides
V. C. Fäseke, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 7261–7264.


22.
Stereoselective Arene-Forming Aldol Condensation: Synthesis of Configurationally Stable Oligo-1,2-naphthylenes
D. Lotter, M. Neuburger, M. Rickhaus, D. Häussinger, C. Sparr*
Angew. Chem. Int. Ed. 2016, 55, 2920–2923.


21.
Direct Transformation of Esters into Arenes with 1,5-Bifunctional Organo­magnesium Reagents
A. Link, C. Fischer, C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 12163–12166.


20.
Scientific Fireworks to Celebrate the 50th Anniversary of the Bürgenstock Conference
C. Sparr*
Angew. Chem. Int. Ed. 2015, 54, 8594–8596.

19.
Organocatalytic Atroposelective Aldol Condensation: Synthesis of Axially Chiral Biaryls by Arene Formation
A. Link, C. Sparr*
Angew. Chem. Int. Ed. 2014, 53, 5458–5461.



Before Basel:
18.
Molecular Design Exploiting a Fluorine gauche Effect as a Stereoelectronic Trigger
Y. P. Rey, L. E. Zimmer, C. Sparr, E.-M. Tanzer, W. B. Schweizer, H. M. Senn,* S. Lakhdar,* R. Gilmour*
Eur. J. Org. Chem. 2014, 1202–1211.

17.
Syntheses, Receptor Bindings, in vivo Stabilities and Biodistributions of DOTA-Neurotensin(8–13) Derivatives Containing β-Amino Acid Residues – A Lesson about the Importance of Animal Experiments
C. Sparr, N. Purkayastha, T. Yoshinari, D. Seebach,* S. Maschauer, O. Prante,* H. Hübner, P. Gmeiner, B. Kolesinska, R. Cescato, B. Waser, J. C. Reubi
Chem. Biodiversity 2013, 10, 2101–2121.

16.
Improved Efficacy of Fosmidomycin against Plasmodium and Mycobacterium Species by Combination with the Cell-Penetrating Peptide Octaarginine
C. Sparr, N. Purkayastha, B. Kolesinska, M. Gengenbacher, B. Amulic, K. Matuschewski, D. Seebach,* F. Kamena*
Antimicrob. Agents Chemother. 2013, 57, 4689–4698.

15.
Synthesis of (–)-Hennoxazole A: Integrating Batch and Flow Chemistry Methods
A. Fernández, Z. G. Levine, M. Baumann, S. Sulzer-Mossé , C. Sparr, S. Schläger, A. Metzger, I. R. Baxendale, S. V. Ley*
Synlett 2013, 514–518.

14.
Exploiting Fluorine Conformational Effects in Organocatalyst Design: The Fluorine-Iminium Ion Gauche Effect
C. Sparr, L. E. Zimmer, R. Gilmour*
in Asymmetric Synthesis II: More Methods and Applications 2012, 117–124.

13.
Synthesis of Enantiomerically Enriched 3-Amino-2-oxindoles through a Palladium Mediated Asymmetric Intramolecular Arylation of α-Ketimino Amides
P. Tolstoy, S. X. Y. Lee, C. Sparr, S. V. Ley*
Org. Lett. 2012, 14, 4810–4813.

12.
Preparation and Characterization of New C2- and C1- Symmetric Nitrogen, Oxygen, Phosphorous, and Sulfur Derivatives and Analogs of TADDOL. Part III
D. Seebach,* A. K. Beck, H.-U. Bichsel, A. Pichota, C. Sparr, R. Wünsch, W. B. Schweizer
Helv. Chim. Acta 2012, 95, 1303–1324.

11.
1,2-Oxazine N-Oxides as Catalyst Resting States in Michael Additions of Aldehydes to Nitro Olefins Organocatalyzed by α,α-Diphenylprolinol Trimethylsilyl Ether
D. Seebach,* X. Sun, C. Sparr, M.-O. Ebert, W. B. Schweizer, A. K. Beck
Helv. Chim. Acta 2012, 95, 1064–1078.

10. Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design
L. E. Zimmer, C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2011, 50, 11860–11871.

9.
Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantio­selective Organo­catalytic Reaction Design
C. Sparr,* R. Gilmour*
Angew. Chem. Int. Ed. 2011, 50, 8391–8395.


8.
Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan’s Stereo­electronic Hypothesis
C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn,* R. Gilmour*
Chem. Eur. J. 2011, 17, 8850–8857.

7.
Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies
C. Sparr, R. Gilmour*
Angew. Chem. Int. Ed. 2010, 49, 6520–6523.

6.
Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes Organocatalyzed by Diarylprolinol or Imidazolidinone Derivatives – Is There an '(E)/(Z)-Dilemma'?
D. Seebach,* R. Gilmour,* U. Groselj, G. Deniau, C. Sparr, M.-O. Ebert, A. K. Beck, L. B. McCusker, D. Sisak, T. Uchimaru
Helv. Chim. Acta 2010, 93, 603–634.

5.
A Concise Synthesis of (S)-2-(Fluoro­diphenylmethyl)pyrrolidine: A Novel Organocatalyst for the Stereoselective Epoxidation of α,β-Unsaturated Aldehydes
C. Sparr, E.-M. Tanzer, J. Bachmann, R. Gilmour*
Synthesis 2010, 1394–1397.

4.
Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Anti­malarial Parasite Chemotherapy
C. Bucher, C. Sparr, W. B. Schweizer, R. Gilmour*
Chem. Eur. J. 2009, 15, 7637–7647.

3.
The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis
C. Sparr, W. B. Schweizer, H. M. Senn, R. Gilmour*
Angew. Chem. Int. Ed. 2009, 48, 3065–3068.

2.
Synthesis of a Novel γ-Folic Acid-Nτ-Histidine Conjugate Suitable for Labeling with 99mTc and 188Re
C. Sparr, U. Michel, R. E. Marti, C. Müller, R. Schibli, R. Moser, V. Groehn*
Synthesis 2009, 787–792.

1.
Folate-Conjugates and Corresponding Metal-Chelate Complexes for Use in Diagnostic Imaging and Radiotherapy
R. Moser, R. Schibli, C. M. Müller, V. Groehn, U. Michel, C. Sparr, T. L. Mindt
Worldwide Patent 2008, WO2008125618.