Publications


Motility, force generation, and energy consumption of unicellular parasites
Axel Hochstetter and Thomas Pfohl
Trends in Parasitology 32, 531-541 (2016)

Formation of actin networks in microfluidic concentration gradients
Natalja Strelnikova, Florian Herren, Cora-Ann Schoenenberger, and Thomas Pfohl
Front. Mater. 3, 20, doi: 10.3389/fmats.2016.00020 (2016)

Characterization of mechano-sensitive nano-containers for targeted vasodilation
Marzia Buscema, Hans Deyhle, Thomas Pfohl, Simone Hieber, Andreas Zumbuehl, and Bert Müller
Proc. SPIE 9797, 97970S (2016)

Trapping, entrainment and synchronization of semiflexible polymers in narrow, asymmetric confinements
Zoe Swank, Siddharth Deshpande and Thomas Pfohl
Soft Matter 12, 87-92 (2016)

Formation of lipid and polymer based gold nanohybrids using a nanoreactor approach
Dominik Witzigmann, Sandro Sieber, Fabiola Porta, Philip Grossen, Andrej Bieri, Natalja Strelnikova, Thomas Pfohl, Cristina Prescianotto-Baschong, and Jörg Huwyler
RSC Adv. 5, 74320-74328 (2015)

Real-time dynamics of emerging actin networks in cell-mimicking compartments
Siddharth Deshpande and Thomas Pfohl
PLoS ONE 10, e0116521, doi: 10.1371/journal.pone.0116521 (2015)

Microfluidics-based single cell analysis reveals drug-dependent motility changes in trypanosomes
Axel Hochstetter, Eric Stellamanns, Siddharth Deshpande, Sravanti Uppaluri, Markus Engstler and Thomas Pfohl
Lab on a Chip 15, 1961-1968 (2015)

Glass-based geometry-induced electrostatic trapping devices for improved scattering contrast imaging of nano-objects
Michael Adrian Gerspach, Nassir Mojarad, Thomas Pfohl, Yasin Ekinci
Microelectron. Eng. 145, 43-48 (2015)



2014


TranslationalMedicine: Nanoscience and Nanotechnology to Improve Patient Care
B. Müller, A. Zumbuehl, M. A. Walter, T. Pfohl, P. C. Cattin, J. Huwyler, S. E. Hieber
in: The Nano-Micro Interface II - Bridging the Micro and Nano Worlds, H. Fecht (ed.), Wiley-VCH, 291-309 (2014)

Optical trapping reveals propulsion forces, power generation and motility efficiency of the unicellular parasites Trypanosoma brucei brucei
Eric Stellamanns, Sravanti Uppaluri, Axel Hochstetter, Niko Heddergott, Markus Engstler, Thomas Pfohl
Scientific Reports 4, 6515 (2014)

Effect of molecular parameters on the architecture and membrane properties of 3D assemblies of amphiphilic copolymers
Dalin Wu, Mariana Spulber, Fabian Itel, Mohamed Chami, Thomas Pfohl, Cornelia G. Palivan, Wolfgang Meier
Macromolecules 47, 5060-5069 (2014)

A chaperonin as protein nanoreactor for atom-transfer radical polymerization
Kasper Renggli, Martin G. Nussbaumer, Raphael Urbani, Thomas Pfohl, Nico Bruns
Angew. Chem. Int. Ed. 53, 1443-1447 (2014)

Understanding biorelevant drug release from a novel thermoplastic capsule by considering microstructural formulation changes during hydration
Zdravka Misic, Raphael Urbani, Thomas Pfohl, Katharina Muffler, Georg Sydow, Martin Kuentz
Pharm Res. 31, 194-203 (2014)



2013


Analysis of complex fluids using microfluidics: the particular case of DNA/polycations assemblies
Adriana C. Toma, Rolf Dootz, Thomas Pfohl
J. Phys. D: Appl. Phys. 46, 114001 (2013)



2012


Trypanosome motion represents an adaptation to the crowded environment of the vertebrate bloodstream
Niko Heddergott, Timothy Krüger, Sujin B. Babu, Ai Wei, Eric Stellamanns, Sravanti Uppaluri, Thomas Pfohl, Holger Stark, Markus Engstler
PLoS Pathogens 8, e1003023 (2012)

Polymer nanoreactors with dual functionality: simultaneous detoxification of peroxynitrite and oxygen transport
Dominik Dobrunz, Adriana C. Toma, Pascal Tanner, Thomas Pfohl, Cornelia G. Palivan
Langmuir 28, 15889-15899 (2012)

Flow loading induces oscillatory trajectories in a bloodstream parasite
Sravanti Uppaluri, Niko Heddergott, Eric Stellamanns, Stephan Herminghaus, Andreas Zöttl, Holger Stark, Markus Engstler, Thomas Pfohl
Biophysical Journal 103, 1162-1169 (2012)

Hierarchical self-assembly of actin in micro-confinements using microfluidics
Siddharth Deshpande, Thomas Pfohl
Biomicrofluidics 6, 034120 (2012)

Monofunctionalized gold nanoparticles stabilized by a single dendrimer form dumbbell structures upon homocoupling
Jens P. Hermes, Fabian Sander, Ulrike Fluch, Torsten Peterle, Damien Thompson, Raphael Urbani, Thomas Pfohl, Marcel Mayor
J. Am. Chem. Soc. 134, 14674-14677 (2012)

X-ray studies of biological matter in microfluidic environments
Sarah Köster, Thomas Pfohl
Mod. Phys. Lett. B 26, 1230018 (2012)

Mobility gradient induces cross-streamline migration of semiflexible polymers
Dagmar Steinhauser, Sarah Köster, Thomas Pfohl
ACS Macro Lett. 1, 541-545 (2012)

African Trypanosomes as model system for functional analyses of microbial motility
Markus Engstler, Niko Heddergott, Tim Krüger, Eric Stellamanns, Sravanti Uppaluri, Thomas Pfohl
in: Nature-inspired fluid mechanics, Cameron Tropea and Horst Bleckmann (eds).
Notes on numerical fluid mechanics and multidisciplinary design (NNFM) 119, 43-61 (2012)

Small-angle X-ray scattering (SAXS) and wide-angle X-ray scattering (WAXS) of supramolecular assemblies
Adriana C. Toma, Thomas Pfohl
in: Supramolecular Chemistry: from Molecules to Nanomaterials, J. W. Steed and P. A. Gale (eds). John Wiley & Sons Ltd, Chichester, 437-450 (2012)

Droplet based microfluidics
Ralf Seemann, Martin Brinkmann, Thomas Pfohl, Stephan Herminghaus
Rep. Prog. Phys. 75, 016601 (2012)



2011


Imaging of vascular smooth muscle cells with soft X-ray spectromicroscopy
Julia Sedlmair, Sophie-Charlotte Gleber, Semra Öztürk Mert, Michael Bertilson, Olov von Hofsten, Jürgen Thieme, Thomas Pfohl
Microscopy and Microanalysis 17, 991-1001 (2011)

Gold nanoparticles stabilized by thioether dendrimers
Jens P. Hermes, Fabian Sander, Torsten Peterle, Raphael Urbani, Thomas Pfohl, Damien Thompson, Marcel Mayor
Chem. Eur. J. 17, 13473-13481 (2011)

X-ray spectromicroscopy of biomolecular matter and soils
Julia Sedlmair, Sophie-Charlotte Gleber, Semra Öztürk, Thomas Pfohl, Peter Guttmann, Sue Wirick, Jürgen Thieme
The 10th International Conference on X-Ray Microscopy, AIP Conf. Proc. 1365, 369-372 (2011)

PAMAM6 dendrimers and DNA: pH dependent "beads-on-a-string" behavior revealed by small angle X-ray scattering
Rolf Dootz, Adriana Cristina Toma, Thomas Pfohl
Soft Matter 7, 8343-8351 (2011)

The impact of heparin intercalation at specific binding sites in telopeptide-free collagen type I fibrils
Dimitar R. Stamov, T. A. Khoa Nguyen, Heather M. Evans, Thomas Pfohl, Carsten Werner, Tilo Pompe
Biomaterials 32, 7444-7453 (2011)

Impact of microscopic motility on the swimming behavior of parasites: straighter trypanosomes are more directional
Sravanti Uppaluri, Jan Nagler, Eric Stellamanns, Niko Heddergott, Stephan Herminghaus, Markus Engstler, Thomas Pfohl
PLoS Comput Biol 7, e1002058 (2011)

Phase behavior of vesicle-forming block copolymers in aqueous solutions
Jörg Braun, Nico Bruns, Thomas Pfohl, Wolfgang Meier
Macromolecular Chemistry and Physics 212, 1245-1254 (2011)

Langevin dynamics deciphers the motility pattern of swimming parasites
Vasily Zaburdaev, Sravanti Uppaluri, Thomas Pfohl, Markus Engstler, Rudolf Friedrich, Holger Stark
Phys. Rev. Lett. 106, 208103 (2011)

Tunable silk: using microfluidics to fabricate silk fibers with controllable properties
Michelle E. Kinahan, Emmanouela Filippidi, Sarah Köster, Xiao Hu, Heather M. Evans, Thomas Pfohl, David L. Kaplan, Joyce Wong
Biomacromolecules 12, 1504-1511 (2011)

Structural and dynamic properties of linker histone H1 binding to DNA
Rolf Dootz, Adriana C. Toma, Thomas Pfohl
Biomicrofluidics 5, 024104 (2011)

Direct control of the spatial arrangement of gold nanoparticles in organic-inorganic hybrid superstructures
Jens Hermes, Fabian Sander, Torsten Peterle, Carla Cioffi, Philippe Ringler, Thomas Pfohl, Marcel Mayor
Small 7, 920-929 (2011)

Dynamics of intermediate filament assembly followed in micro-flow by small angle x-ray scattering
Martha E. Brennich, Jens-F. Nolting, Christian Dammann, Bernd Nöding, Susanne Bauch, Harald Hermann, Thomas Pfohl, Sarah Köster
Lab on a Chip 11, 708-716 (2011)



2010


Biophysical Chemistry
Daniel Häussinger and Thomas Pfohl
Chimia 64, 874-876 (2010)

Analyse, Manipulation und Aggregation von biologischen Makromolekülen im mikrofluidischen Scherfluss
Thomas Pfohl
Jahrbuch der Akademie der Wissenschaften zu Göttingen 2009, De Gruyter, 331-336 (2010)

Preparation of monodisperse block copolymer vesicles via flow focusing in microfluidics
Julian Thiele, Dagmar Steinhauser, Thomas Pfohl, Stephan Förster
Langmuir 26, 6860-6863 (2010)



2009


An in vitro model system for cytoskeletal confinement
Sarah Köster and Thomas Pfohl
Cell Motil. Cytoskeleton 66, 771-776 (2009)

In situ formation, manipulation, and imaging of droplet-encapsulated fibrin networks
Heather M. Evans, Enkhtuul Surenjav, Craig Priest, Stephan Herminghaus, Ralf Seemann, Thomas Pfohl
Lab on a Chip 9, 1933-1941 (2009)



2008


Characterization of single semiflexible filaments under geometric constraints
Sarah Köster, Jan Kierfeld, Thomas Pfohl
European Physical Journal E 25, 439-449 (2008)

An in situ study of collagen self-assembly processes
Sarah Köster, Heather M. Evans, Joyce Y. Wong, Thomas Pfohl
Biomacromolecules 9 (1), 199-207 (2008)



2007


Hydrodynamic flow-mediated protein sorting on the cell surface of trypanosomes
Markus Engstler, Thomas Pfohl, Stephan Herminghaus, Michael Boshart, Geert Wiegertjes, Niko Heddergott, Peter Overath
Cell 131, 505-515 (2007)
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Fluctuations of single confined actin filaments
Sarah Köster, Holger Stark, Thomas Pfohl, Jan Kierfeld
Biophysical Reviews and Letters 2 (2), 155-166 (2007)

Highly packed and oriented DNA mesophases identified using in situ microfluidic X-ray microdiffraction
Thomas Pfohl, Alexander Otten, Sarah Köster, Rolf Dootz, Bernd Struth, Heather Evans
Biomacromolecules 8 (7), 2167-2172 (2007)

X-ray microdiffraction on flow-controlled biomolecular assemblies
Heather M Evans, Rolf Dootz, Sarah Köster, Bernd Struth, Thomas Pfohl
Bulletin of the Polish Academy of Sciences: Technical Sciences 55 (2), 217-227 (2007)

Manipulation of monodisperse gel emulsions in microchannels
E. Surenjav, H. Evans, Thomas Pfohl, C. Priest, S. Herminghaus, R. Seemann
In: Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences - The Proceedings of the µTAS 2007 Conference, 7-11 October 2007, Paris Eds. J.-L. Viovy, P. Tabeling, S. Descroix, L. Malaquin, 339-342 (2007)

Rapid prototyping of X-ray microdiffraction compatible continuous microflow foils
Rolf Dootz, Heather Evans, Sarah Köster, Thomas Pfohl
Small 3 (1), 96-100 (2007)

Visualization of flow-aligned type I collagen self-assembly in tunable pH gradients
Sarah Köster, Jamie Leach, Bernd Struth, Thomas Pfohl, Joyce Y. Wong
Langmuir 23, 357-359 (2007)



2005 - 2006


Evolution of DNA compaction in microchannels
Rolf Dootz, Alexander Otten, Sarah Köster, Bernd Struth, Thomas Pfohl
J. Phys.: Condens. Matter 18, S639-S652 (2006)

Raman and surface enhanced Raman microscopy of microstructured PEI/DNA multilayers
Rolf Dootz, Jingjing Nie, Binyang Du, Stephan Herminghaus, Thomas Pfohl
Langmuir 22, 1735 (2006)

AFM study of defect-induced depressions of the smectic-A/air interface
Vincent Designolle, Stephan Herminghaus, Thomas Pfohl, Christian Bahr
Langmuir 22, 363 (2006)

Microaligned collagen matrices by hydrodynamic focusing: controlling the pH-induced self-assembly
Sarah Köster, Jennie B. Leach, Joyce Y. Wong, Thomas Pfohl
MRS Proceedings 898E, 0989-L05-21 (2005)

Brownian motion of actin filaments in confining microchannels
Sarah Köster, Dagmar Steinhauser, Thomas Pfohl
Journal of Physics: Condensed Matter 17, S4091 (2005)

Microfluidics of soft matter investigated by small angle x-ray scattering
Alexander Otten, Sarah Köster, Bernd Struth, Anatoly Snigirev, Thomas Pfohl
Journal of Synchrotron Radiation 12, 745 (2005)



2003 - 2004


Ordered patterns of liquid crystal toroidal defects by microchannel confinement
Myung Chul Choi, Thomas Pfohl, Zhiyu Wen, Youli Li, Mahn Won Kim, Jacob N. Israelachvili, Cyrus R. Safinya
Proceedings of the National Academy of Sciences of the USA (PNAS) 101, 17340 (2004)

Application of microfocussing at a non-specific beamline
Bernd Struth, Anatoly Snigirev, Oleg Konovalov, Alexander Otten, Rainer Gauggel, Thomas Pfohl
SRI 2003 Proceedings, AIP Conference Proceedings 705, 804 (2004)

Trends in microfluidics with complex fluids
Thomas Pfohl, Frieder Mugele, Ralf Seemann, Stephan Herminghaus
ChemPhysChem 4, 1291 (2003)

Structural polymorphism of DNA-dendrimer complexes
Heather M. Evans, Ayesha Ahmad, Kai Ewert, Thomas Pfohl, Ana Martin-Herranz, Robin F. Bruinsma, Cyrus R. Safinya
Phys. Rev. Lett. 91, No. 7, 075501 (2003)

Mikrofluidik mit komplexen Flüssigkeiten
Thomas Pfohl und Stephan Herminghaus
Physik Journal 2 Nr.1, 35 (2003)



2000 - 2002


Biological polyelectrolyte complexes in solution and confined on patterned surfaces
Thomas Pfohl, Youli Li, Joon Heon Kim, Zhiyu Wen, Gerard C. L. Wong, Mahn Won Kim, Ilya Koltover, Cyrus R. Safinya
Colloids & Surfaces A: Physiochemical and Engineering Aspects 198, 613-623 (2002)

Selective surface modification in silicon microfluidic channels for micromanipulation of biological macromolecules
Youli Li, Thomas Pfohl, Joon Heon Kim, Mario Yasa, Zhiyu Wen, Mahn Won Kim, Cyrus R. Safinya
Biomedical Microdevices 3, 239 (2001)

Controlled modification of microstructured silicon surfaces for manipulation and confinement of biopolymers and liquid crystals
Thomas Pfohl, Joon Heon Kim, Mario Yasa, Herb P. Miller, Gerard C. L. Wong, Frank Bringezu, Zhiyu Wen, Les Wilson, Youli Li, Mahn Won Kim, Cyrus R. Safinya
Langmuir 17, 5343 (2001)



1995 - 1999


Influence of the polymer charge density on lipid-polyelectrolyte complexes at the air/water-interface
Kerstin de Meijere, Gerald Brezesinski, Thomas Pfohl, Helmuth Möhwald
J. Phys. Chem. B 103, 8888 (1999)

Influence of ethanol on the thickness and free energy of film formation of DMPC foam films
J. L. Toca-Herrera, H.-J. Müller, R. Krustev, T. Pfohl, H. Möhwald
Colloids and Surfaces A 152, 357 (1999)

Ellipsometric chain length dependence of fatty acid Langmuir monolayers. A head and-tail model
Jordan G. Petrov, Thomas Pfohl, Helmuth Möhwald
J. Phys. Chem. B 103, 3417 (1999)

Critical wetting of a liquid/vapor interface by octane
Thomas Pfohl and Hans Riegler
Phys. Rev. Lett. 82, 783 (1999)

Ellipsometric study of the wetting of air/water interfaces with hexane, heptane, and octane from saturated alkane vapors
Thomas Pfohl, Helmuth Möhwald, Hans Riegler
Langmuir 14, 5285 (1998)

Silicon containing structures at interfaces ­ the wetting behavior of carbohydrate modified Si surfactants on perfluorinated surfaces and the modification of rough metal surfaces by hydrophilic polysiloxane networks
R. Wagner, Y. L. Wu, L. Richter, T. Pfohl, S. Siegel, J. Weissmüller, J. Reiners, M. Stelzle, R. Fröhlich
Chem. Engineering & Technology 21, 172 (1998)

Influence of the molecular ordering on the wetting of SiO2/air interfaces by alkanes
Christoph Merkl, Thomas Pfohl, Hans Riegler
Phys. Rev. Lett. 79, 4625 (1997)

An ellipsometric study of the surface freezing of liquid alkanes
Thomas Pfohl, David Beaglehole, Hans Riegler
Chem. Phys. Lett. 260, 82 (1996)

Ellipsometry and x-ray reflectivity studies on monolayers of phosphatidylethanolamine and phosphatidylcholine in contact with n-dodecane, n-hexadecane, and bicyclohexyl
Martin Thoma, Michael Schwendler, Hubert Baltes, Christiane A. Helm, Thomas Pfohl, Hans Riegler, Helmuth Möhwald
Langmuir 12, 1722 (1996)

Thermodynamic relation of an insoluble monolayer at the oil/water interface and at the air/water interface in contact with oil
Martin Thoma, Thomas Pfohl, Helmuth Möhwald
Langmuir 11, 2881 (1995)