Prof. Dr. Dennis G. Gillingham

Principal Investigator

Career

Full CV is available here

Bibliography

2017

  • Dennis G. Gillingham and Basilius Sauter, «Genomic studies reveal new aspects of the biology of DNA damaging agents», ChemBioChem 2017. doi:10.1002/cbic.201700520.

  • Stefanie Geigle, Laura A. Wyss, Shana J. Sturla and Dennis G. Gillingham, «Copper carbenes alkylate guanine chemoselectively through a substrate directed reaction», Chemical Science 2017, 8, 499─506. doi:10.1039/c6sc03502g.

2016

  • Dennis G. Gillingham, «The role of boronic acids in accelerating condensation reactions of α-effect amines with carbonyls», Organic & Biomolecular Chemistry 2016, 14, 7606─7609. doi:10.1039/C6OB01193D.

  • Na Fei, Basilius Sauter and Dennis G. Gillingham, «The pKa of Bronsted acids controls their reactivity with diazo compounds.», Chemical Communications 2016, 52, 47, 7501─7504. doi:10.1039/c6cc03561b.

  • Cedric J. Stress, Pascal Schmidt and Dennis G. Gillingham, «Comparison of boron-assisted oxime and hydrazone formations leads to the discovery of a fluorogenic variant.», Organic & Biomolecular Chemistry 2016, 14, 24, 5529─5533. doi:10.1039/C6OB00168H.

  • Dennis G. Gillingham, Stefanie Geigle and O. Anatole Lilienfeld, «Properties and reactivity of nucleic acids relevant to epigenomics, transcriptomics, and therapeutics», Chemical Society Reviews 2016, 45, 9, 2637─2655. doi:10.1039/c5cs00271k.

2015

  • Kiril Tishinov and Dennis G. Gillingham, «Synthesis of New Alkylated Mononucleotide Analogues and Their Repair Proficiency by the Prokaryotic DNA Repair Protein AlkB», Synlett 2015, 26, 19, 2720─2723. doi:10.1055/s-0035-1560491.

  • Daniel Bachmann, Pascal Schmidt, Stefanie Geigle, Antoinette Chougnet, Wolf-Dietrich Woggon and Dennis G. Gillingham, «Modular Ligands for Dirhodium Complexes Facilitate Catalyst Customization», Advanced Synthesis & Catalysis 2015, 357, 9, 2033─2038. doi:10.1002/adsc.201500050.

  • Dennis G. Gillingham and Ramla Shahid, «Catalysts for RNA and DNA modification», Current Opinion in Chemical Biology 2015, 25, 110─114. doi:10.1016/j.cbpa.2014.12.025.

  • Pascal Schmidt, Cedric J. Stress and Dennis G. Gillingham, «Boronic acids facilitate rapid oxime condensations at neutral pH», Chemical Science 2015, 6, 6, 3329─3333. doi:10.1039/C5SC00921A.

2014

  • Pascal Schmidt, Linna Zhou, Kiril Tishinov, Kasper Zimmermann and Dennis G. Gillingham, «Dialdehydes Lead to Exceptionally Fast Bioconjugations at Neutral pH by Virtue of a Cyclic Intermediate», Angewandte Chemie International Edition 2014, 53, 41, 10928─10931. doi:10.1002/anie.201406132.

  • Na Fei, Seraina Bluemli, Benoit-Joseph Lavantie, Lorenzo D. Bizzini, Kasper Zimmermann, Urs Jenal and Dennis G. Gillingham, «Catalytic carbene transfer allows the direct customization of cyclic purine dinucleotides», Chemical Communications 2014, 50, 62, 8499─8502. doi:10.1039/C4CC01919A.

2013

  • Daniel Bachmann, Christopher C. Witter and Dennis G. Gillingham, «Stereoselective Heck Reactions with Vinyl Sulfoxides, Sulfides and Sulfones», Advanced Synthesis & Catalysis 2013, 355, 18, 3703─3707. doi:10.1002/adsc.201300678.

  • Dennis G. Gillingham and Na Fei, «Catalytic X-H insertion reactions based on carbenoids», Chemical Society Reviews 2013, 42, 12, 4918─4931. doi:10.1039/C3CS35496B.

  • Dennis G. Gillingham and Kiril Tishinov, «Synthesis of Nucleic Acid Polymers with Non-Canonical Nucleobases», Synlett 2013, 24, 8, 893─897. doi:10.1055/s-0032-1318493.

  • Kiril Tishinov, Na Fei and Dennis G. Gillingham, «Cu(I)-catalysed N-H insertion in water: a new tool for chemical biology», Chemical Science 2013, 4, 12, 4401─4406. doi:10.1039/C3SC51363G.

2012

  • Kiril Tishinov, Kristina Schmidt, Daniel Häusinger and Dennis G. Gillingham, «Structure-Selective Catalytic Alkylation of DNA and RNA», Angewandte Chemie International Edition 2012, 51, 12000─12004. doi:10.1002/anie.201205201.

  • Dennis G. Gillingham, Alexandre Martinez and Zbigniew Pianowski, «A Report from the 47th EUCHEMS Conference on Stereochemistry: The Bürgenstock Conference», Chimia 2012, 66, 873─875. doi:10.2533/chimia.2012.873.

  • Pierre Stallforth, Stefan Matthies, Alexander Adibekian, Dennis G. Gillingham, Donald Hilvert and Peter Seeberger, «A De novo chemoenzymatic synthesis of sialic acid», Chemical Communications 2012, 48, 11987─11989. doi:10.1039/c2cc37305j.

Older

  • Clemens Mayer, Dennis G. Gillingham, Thomas R. Ward and Donald Hilvert, «An artificial metalloenzyme for olefin metathesis», Chemical Communications 2011, 47, 12068─12070. doi:10.1039/C1CC15005G.

  • Dennis G. Gillingham, Pierre Stallforth, Alexander Adibekian, Peter Seeberger and Donald Hilvert, «A Chemoenzymatic Synthesis of Differentially Protected 3-Deoxysugars», Nature Chemistry 2010, 2, 102─105. doi:10.1038/nchem.504.

    • This article was also featured in the News and Views section: Benjamin G. Davis, «Enzyme catalysis: Sweet flexibility», Nature Chemistry 2010, 2, 85─86. doi:10.1038/nchem.529
  • Jörg M. Serafimov, Dennis G. Gillingham, Simon Kuster and Donald Hilvert, «The Putative Diels-Alderase Macrophomate Synthase is an Efficient Aldolase», Journal of the American Chemical Society 2008, 130, 7798─7799. doi:10.1021/ja8017994.

  • Yunmi Lee, Katsuhiro Akiyama, Dennis G. Gillingham, M. Kevin Brown and Amir H. Hoveyda, «Highly Site- and Enantioselective Cu-Catalyzed Allylic Alkylation Reactions with Easily Accessible Vinylaluminum Reagents», Journal of the American Chemical Society 2008, 130, 446─447. doi:10.1021/ja0782192.

  • Dennis G. Gillingham and Amir H. Hoveyda, «Chiral N-Heterocyclic Carbenes in Natural Product Synthesis: Application of Ru-Catalyzed Asymmetric Ring-Opening/Cross-Metathesis and Cu-Catalyzed Allylic Alkylation to Total Synthesis of Baconipyrone C», Angewandte Chemie International Edition 2007, 46, 3860─3864. doi:10.1002/anie.200700501.

  • Dennis G. Gillingham, Osamu Kataoka, Steven B. Garber and Amir H. Hoveyda, «Efficient Enantioselective Synthesis of Functionalized Tetrahydropyrans by Ru-Catalyzed Asymmetric Ring-Opening Metathesis/Cross-Metathesis (AROM/CM)», Journal of the American Chemical Society 2004, 126, 12288─12290. doi:10.1021/ja0458672.

  • Amir H. Hoveyda, Dennis G. Gillingham, Joshua J. VanVeldhuizen, Osamu Kataoka, Steven B. Garber, Jason S. Kingsbury and Joseph P. Harrity, «Ru Complexes Bearing Bidentate Carbenes: From Innocent Curiosity to Uniquely Effective Catalysts for Olefin Metathesis», Organic & Biomolecular Chemistry 2004, 2, 8─23. doi:10.1039/b311496c.

  • Joshua J. VanVeldhuizen, Dennis G. Gillingham, Stephen B. Garber, Osamu Kataoka and Amir H. Hoveyda, «Chiral Ru-based Complexes for Asymmetric Olefin Metathesis: Enhancement of Catalyst Activity through Steric and Electronic Modifications», Journal of the American Chemical Society 2003, 125, 12502─12508. doi:10.1021/ja0302228.

Contact

Fon: +41 (0)61 207 11 48

Fax: +41 (0)61 207 09 76

Department of Chemistry, University of Basel St. Johanns-Ring 19 CH-4056 Basel Switzerland