Artificial Metalloenzymes Laboratory

Endowing Organomettallic Chemistry with a (Genetic) Memory
Artificial metalloenzymes result from the incorporation of an abiotic cofactor within a protein scaffold. Such hybrid catalysts combine features reminiscent of both homogeneous catalysts and enzymes.

Research

Merging organometallic chemistry with biotechnology.

The group

Recent publications

Jeschek M et al. Directed evolution of artificial metalloenzymes for in vivo metathesis. Nature 2016 Aug 29. http://dx.doi.org/10.1038/nature19114

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Lay summary

"Catalysis is the concept which best captures the Spirit of Chemistry: the Miracle of consumption and regeneration."

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